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Collagen Injectable Fillers

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What is collagen?
Collagen, a naturally occurring fibrous protein found in both humans and animals, provides structural support for bones, skin, tendons, ligaments, and blood vessels and is the most abundant protein in the body.

What is Collagen Replacement Therapy®?
Zyderm and Zyplast collagen implants, also known as Collagen Replacement Therapy, are safe, non-surgical treatments in which highly purified bovine collagen is injected into the skin to replenish the skin's natural collagen.

Where does bovine collagen come from?
Zyderm and Zyplast collagen implants are composed of highly purified bovine dermal tissue. This material is obtained from the hides of steers within a closed herd.

What is a closed herd?
A closed herd is defined as one in which:

  • there is no case of Bovine Spongiform Encephalopathy (BSE);
  • there is no feeding of mammalian-derived (animal by-products) protein;
  • there is a fully documented breeding history;
  • there is a fully documented veterinary monitoring;
  • each animal is monitored and traceable; and
  • genetic material has been introduced only from herds with the same BSE-free status.

Why would one choose Collagen Replacement Therapy?
When a person smiles, frowns, or squints, stress is placed on the collagen in the skin, wearing it down and resulting in the formation of facial lines and wrinkles. Zyderm and Zyplast collagen injections can improve the appearance of the skin by reducing lines and wrinkles.

How long have people been using bovine-based collagen?
Zyderm and Zyplast bovine based collagen has been the preferred source for injectable collagen since 1981. Over 1.5 million patients have been treated with Zyderm and Zyplast collagen implants worldwide.

Has bovine-based collagen been approved by the FDA?
Yes. Zyderm and Zyplast collagen implants made by INAMED Aesthetics, are FDA-approved collagens for facial injection.

How do we know INAMED Aesthetics' bovine-based collagen facial injections are safe and free of contamination?
INAMED Aesthetics manufactures a highly purified form of bovine collagen, derived from a USDA-certified and carefully monitored closed herd of cattle in California.

How is collagen injected?
Bovine collagen in injected through a tiny needle just below the surface of the skin to smooth wrinkles or define the lip border.

What are the indications for treatment?
Fine to deep wrinkles, frown lines, smile lines, crow's feet, lip border, acne and other scars.

How long does a treatment last?
Treatments generally last 3-6 months.

What are the advantages to collagen treatment?
Collagen treatment requires minimal recovery and is relatively painless. Results are immediate and the product does not "migrate." Zyderm/Zyplast injectable collagen contains lidocaine for greater patient comfort.



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